For Medical Professionals, Researchers and Curious Minds
Introduction.
Tanycytes are no longer just structural bystanders in the brain.
These specialized glial cells, lining the third ventricle of the hypothalamus, are emerging as key regulators of:
- Hormone transport,
- Neuroendocrine communication, and
- Metabolic balance.
What Are Tanycytes?
Tanycytes are unique glial cells forming part of the brain–CSF interface, strategically located at the hypothalamic floor.
Their specialized extensions allow them to sense, capture, and shuttle hormones between the brain and bloodstream.
Hormone Gatekeepers of the Brain
How Tanycytes Regulate Hormone Sensing in the Brain
Recent research reveals that tanycytes:
- Regulate hormone access to hypothalamic neurons
- Influence neurogenesis and energy metabolism
- Play roles in thyroid hormone sensing and leptin signaling
- Bridge neuronal and endocrine systems via barrier modulation
Clinical Relevance.
This eBook explores how tanycytes may impact conditions such as:
- Obesity and metabolic syndromes
- Thyroid dysfunction
- Neuroplasticity-related disorders
By understanding how tanycytes coordinate hormonal signals, we open new avenues for therapeutic targeting in neuroendocrine diseases.
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Inside the eBook:
- Tanycyte classification & functions
- Hormone transport mechanisms
- Tanycytes in neurodevelopment and regeneration
- Clinical connections and future therapies
Dr. H.K. Saboowala, M.B.B.S. (Bom), M.R.S.H. (London), F.F.M. (UK)
Unlocks the brain’s hidden highways in this comprehensive review of tanycytic function.
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Medical Review.
This eBook offers a focused look at tanycytes—glial cells that regulate hormone sensing and transport in the hypothalamus. Their role in linking the brain and endocrine system is clearly explained, highlighting their clinical relevance in metabolic and thyroid disorders. A valuable resource for understanding this emerging neuroendocrine pathway.
– Dr. A. Mehra, MD, DM (Neuroendocrinology)
Consultant Neuroendocrinologist
Thank You Note.
Thank you for taking the time to explore this comprehensive overview of tanycytic function in the brain.
Understanding the intersection of glial biology and hormone signalling is key to unlocking novel therapies in neuroendocrine disorders.
With appreciation,
Dr. Hakim K. SaboowalaM.B.B.S. (Bom), M.R.S.H. (London), F.F.M. (UK)
https://drhakimemedivault.com
